Welcome to the community. Is APEX disconnected before the console is turned on? It expects this and there can be startup issues if connected before the console is on.
About your question, there are ways to verify the state of your hardware to help isolate the cause.
We can check if the controller is authenticating using direct connection, this is needed for your mouse and keyboard to work. To do this, please remove the hub and then disconnect and reconnect APEX to the console with the controller directly connected to APEX while watching APEX's startup light sequence. Do you see 4 green lights during this sequence? For reference the startup light sequence should look similar to this:
red, green, blue
red
green, green, green, green
red
If you do not see 4 green lights at startup and you have spare data cables it may help to test these spare cables with the controller.