I just tried Uncharted. Was a little awkward. The way the analog stick works in the game makes for some weird controls with WASD.
I also find the ingame aiming so slow. I don't think this is anything we can speed up. I put game sensitivity to max, and have my mouse on max dpi, but it still just slugs along.
I'm about to start fighting people, so we'll see how that performs shortly.
One idea I did have, but haven't been able to test it yet, is I mapped square to mousewheel up, and triangle to mouse wheel down. So I can do combos by flicking the mousewheel up and down. Also mapped them to keys for when I need to hold or tap them.