Titan Two is used in sponsored global tournaments, e.g Activision uses them for the CoD world champs. There are no reports of anyone ever being banned for using one. It's also very easy to obfuscate input by randomising input timing.
Keep in mind that for console anticheat software to scan for input heuristics, you need a tonne of dedicated server-side resources sniffing packets from EVERY player, logging and analysing that data. It's not done client-side, like it is on PC because it has no access to the operating system, RAM, network packets etc. The cost far outweighs the benefit, so they're not even looking for it. Again, it can be randomised anyway to look like natural input.
Long story short, there's very little to worry about using devices like Cronus or Titan. But, the m/kb experience is far inferior to XIM.