Used the Nexus on The Division last night and the biggest problem I had was with weapons that needed an aux config when I played with the Xim Apex.
Using these weapons with the Nexus was not really playable.
For example on my Deadeye gear build I have to use a bolt action sniper rifle, and you need to use a scope with high crit damage (i.e. an assault rifle scope). This is really sluggish but I overcame it with an aux config on the Apex.
On the Nexus I can't use an aux config and increasing the motion sensitivity is not practical as I would be switching weapons.
I realize it was not the best game to start learning with the Nexus ... it's fun to play with, really hoping to get support for games like Forza in the near future
Update: Have to say that this was in no way meant to be a criticism of the Nexus. I was just pointing out the differences that I felt between playing with Apex and Nexus on a game with bad mechanics.
I've been playing with the Nexus for a few days now and I'm liking what I'm experiencing.
The trigger mapping feature is pure genius, thank you for that one OBsIV

I know a fix is coming for the manager disconnects but I hope it's soon ... it's a wee bit frustrating constantly having to connect.